The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2007

Filed:

Jun. 04, 2003
Applicants:

Merouane Bencherif, Winston-Salem, NC (US);

Craig Harrison Miller, Winston-Salem, NC (US);

Gregory D. Hawkins, Winston-Salem, NC (US);

Balwinder S. Bhatti, Winston-Salem, NC (US);

Inventors:

Merouane Bencherif, Winston-Salem, NC (US);

Craig Harrison Miller, Winston-Salem, NC (US);

Gregory D. Hawkins, Winston-Salem, NC (US);

Balwinder S. Bhatti, Winston-Salem, NC (US);

Assignee:

Targacept, Inc., Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 451/00 (2006.01); A61K 31/55 (2006.01);
U.S. Cl.
CPC ...
Abstract

Patients susceptible to or suffering from disorders, such as central nervous system disorders, which are characterized by an alteration in normal neurotransmitter release, such as dopamine release (e.g., Parkinsonism, Parkinson's Disease, Tourette's Syndrome, attention deficient disorder, or schizophrenia), are treated by administering a 1-aza-2-(3-pyridyl)bicyclo[2.2.1]heptane, a 1-aza-2-(3-pyridyl)bicyclo[2.2.2]octane, a 1-aza-2-(3-pyridyl)bicyclo[3.2.1]octane, a 1-aza-2-(3-pyridyl)bicyclo[3.2.2]nonane, a 1-aza-7-(3-pyridyl) bicyclo[2.2.1]heptane, a 1-aza-3-(3-pyridyl)bicyclo[3.2.2]nonane, or a 1-aza-7-(3-pyridyl)bicyclo[3.2.2]nonane. The compounds can exist as individual stereoisomers, racemic mixtures, diastereomers and the like.


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