The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2007
Filed:
Feb. 17, 2003
Simon E Ward, Harlow, GB;
Simon E Ward, Harlow, GB;
Glaxo Group Limited, Greenford, Middlesex, GB;
Abstract
Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed: wherein: A is optionally substituted phenyl, naphthyl, indolyl, quinolinyl, quinazolinyl, indazolyl, isoquinolinyl or benzofuranyl; X is carbon, Y is CH and is a double bond; or X is CH, Y is CHor oxygen and is a single bond; or X is nitrogen, Y is CHand is a single bond; R 1 is halogen, cyano, or Calkoxy; a is 0,1, 2 or 3 ; b is 0 or 1 ; R 2 is hydrogen, Calkyl, Calkanoyl, fluoroCalkanoyl, Calkylsulfonyl, fluoroCalkylsulfonyl, carbamoyl, Calkylcarbamoyl or arylCalkyl; and R 3 , together with the nitrogen atom to which it is attached, forms an optionally substituted 5 to 7 membered heterocyclic group fused to the benzene ring. Methods of preparing the compounds and uses of the compounds in therapy, in particular for a CNS disorder such as depression or anxiety, are also disclosed.