The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 08, 2007
Filed:
Sep. 01, 2000
Smadar Cohen, Beer Sheva, IL;
Ayelet Dar, Rehovot, IL;
Sharon Etzion, Beer Shevea, IL;
Anat Perets, Bet-Shemesh, IL;
Sigalit Shaprut, Beer Sheva, IL;
Jonathan Leor, Gane′ Tikva, IL;
Smadar Cohen, Beer Sheva, IL;
Ayelet Dar, Rehovot, IL;
Sharon Etzion, Beer Shevea, IL;
Anat Perets, Bet-Shemesh, IL;
Sigalit Shaprut, Beer Sheva, IL;
Jonathan Leor, Gane′ Tikva, IL;
Ben-Gurion University of the Negev Research & Development Authority, Beer-Sheva, IL;
Abstract
The invention is directed to tissue-engineered biografts, methods for preparing the biografts of the invention, and methods for repairing a damaged myocardium in a mammal. The methods of the invention can include providing a three-dimensional porous polysaccharide matrix; introducing mammalian cells into said matrix; growing said cells in said matrix in vitro, until a tissue-engineered biograft is formed; and transplanting the tissue-engineered biograft onto myocardial tissue or myocardial scar tissue of said mammal. The tissue-engineered biograft of the invention can form a contracting tissue. The methods of the invention can optionally include removing scar tissue or dead tissue from the site of implantation prior to transplanting the biograft.