The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 08, 2007

Filed:

Dec. 15, 2004
Applicants:

Bruce P. Mosier, San Francisco, CA (US);

Robert W. Crocker, Fremont, CA (US);

Kamlesh D. Patel, Dublin, CA (US);

Cindy K. Harnett, Livermore, CA (US);

Inventors:

Bruce P. Mosier, San Francisco, CA (US);

Robert W. Crocker, Fremont, CA (US);

Kamlesh D. Patel, Dublin, CA (US);

Cindy K. Harnett, Livermore, CA (US);

Assignee:

Sandia National Laboratories, Livermore, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01F 1/37 (2006.01);
U.S. Cl.
CPC ...
Abstract

An apparatus that couples automated injection with flow feedback to provide nanoliter accuracy in controlling microliter volumes. The apparatus comprises generally a source of hydraulic fluid pressure, a fluid isolator joined to the outlet of the hydraulic pressure source and a flow sensor to provide pressure-driven analyte metering. For operation generally and particularly in microfluidic systems the hydraulic pressure source is typically an electrokinetic (EK) pump that incorporates gasless electrodes. The apparatus is capable of metering sub-microliter volumes at flowrates of 1–100 μL/min into microsystem load pressures of up to 1000–50 psi, respectively. Flowrates can be specified within 0.5 μL/min and volumes as small as 80 nL can be metered.


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