The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2007
Filed:
Sep. 21, 2004
James Sheppeck, Newtown, PA (US);
John L. Gilmore, Yardley, PA (US);
Xiao-tao Chen, Furlong, PA (US);
Xiaohua He, Hockessin, DE (US);
James Sheppeck, Newtown, PA (US);
John L. Gilmore, Yardley, PA (US);
Xiao-Tao Chen, Furlong, PA (US);
Xiaohua He, Hockessin, DE (US);
Bristol Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention describes novel 1,3-dihydro-imidazol-2-one or 1,3-dihydro-imidazol-2-thione compounds of formula (I): or a stereoisomer or pharmaceutically acceptable salt or solvate thereof, wherein A, L R, R, Rand Rare defined in the present specification, which are useful as selective inhibitors of MMP, TACE, aggrecanase or a combination thereof. This invention also relates to pharmaceutical compositions comprising these compounds and methods of using the same.