The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2007
Filed:
Sep. 19, 2002
Suzanne Metz, Chesterfield, MO (US);
Michael Clare, Skokie, IL (US);
Joyce Z. Crich, Glenview, IL (US);
Timothy J. Hagen, Gurnee, IL (US);
Gunnar J. Hanson, Skokie, IL (US);
He Huang, Northbrook, IL (US);
Stephen C. Houdek, Des Plaines, IL (US);
Michael A. Stealey, Libertyville, IL (US);
Michael L. Vazquez, Ballwin, MO (US);
Richard M. Weier, Lake Bluff, IL (US);
Xiangdong Xu, Gurnee, IL (US);
Suzanne Metz, Chesterfield, MO (US);
Michael Clare, Skokie, IL (US);
Joyce Z. Crich, Glenview, IL (US);
Timothy J. Hagen, Gurnee, IL (US);
Gunnar J. Hanson, Skokie, IL (US);
He Huang, Northbrook, IL (US);
Stephen C. Houdek, Des Plaines, IL (US);
Michael A. Stealey, Libertyville, IL (US);
Michael L. Vazquez, Ballwin, MO (US);
Richard M. Weier, Lake Bluff, IL (US);
Xiangdong Xu, Gurnee, IL (US);
Other;
Abstract
The present invention relates to compounds of Formula I:wherein A is (CH)-Q-(CH), wherein each CHmay be independently substituted with one or more substitution selected from the group consisting of: hydroxy, halo, alkoxy, lower alkyl, amino, aminoalkyl, alkylamino, alkenyl, and alkynyl; B is a 5 or 6 membered heteroaryl, or aryl, optionally saturated, or optionally substituted with R, R, or R; X is selected from the group consisting of: N and C; and Y and Z are independently selected from the group consisting of: N, C, CH, CR, S, and O; compositions comprising such compounds, intermediates thereof, methods of making such compounds, and methods for treating cancer, inflammation, and inflammation-associated disorders, such as arthritis.