The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2007
Filed:
Oct. 21, 2004
Michael G. Rosenfeld, San Diego, CA (US);
Christopher K. Glass, San Diego, CA (US);
David W. Rose, San Diego, CA (US);
Joseph Torchia, London, CA;
Michael G. Rosenfeld, San Diego, CA (US);
Christopher K. Glass, San Diego, CA (US);
David W. Rose, San Diego, CA (US);
Joseph Torchia, London, CA;
The Regents of the University of California, Oakland, CA (US);
Abstract
The present invention provides a substantially purified nucleic acid molecule encoding a p/CIP polypeptide, which regulates the activity of CBP/p300-dependent transcription factors. The invention also provides a substantially purified p-CIP polypeptide and active fragments thereof. In addition, the invention provides methods of identifying an effective agent that alters the association of a p/CIP polypeptide with a second protein. Further provided herein are methods of selectively inhibiting signal transduction pathways using an active fragment of a p/CIP polypeptide or a nucleic acid molecule encoding such an acive fragment.