The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2007
Filed:
Feb. 18, 2004
Andrew C. Hiatt, San Diego, CA (US);
Julian K.-c. MA, London, GB;
Thomas Lehner, Herts, GB;
Keith E. Mostov, San Francisco, CA (US);
Andrew C. Hiatt, San Diego, CA (US);
Julian K.-C. Ma, London, GB;
Thomas Lehner, Herts, GB;
Keith E. Mostov, San Francisco, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The immunoglobulins of the present invention are useful therapeutic immunoglobulins against mucosal pathogens such as. The immunoglobulins contain a protection protein that protects the immunoglobulins in the mucosal environment. The invention also includes the greatly improved method of producing immunoglobulins in plants by producing the protection protein in the same cell as the other components of the immunoglobulins. The components of the immunoglobulin are assembled at a much improved efficiency. The method of the invention allows the assembly and high efficiency production of such complex molecules. The invention also contemplates the production of immunoglobulins containing protection proteins in a variety of cells, including plant cells, that can be selected for useful additional properties. The use of immunoglobulins containing protection proteins as therapeutic antibodies against mucosal and other pathogens is also contemplated.