The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 2007
Filed:
Feb. 06, 2004
Kenneth J. Holroyd, Plymouth Meeting, PA (US);
Roy C. Levitt, Plymouth Meeting, PA (US);
W. Lee Maloy, Plymouth Meeting, PA (US);
Jamila Louahed, Plymouth Meeting, PA (US);
Mike Mclane, Plymouth Meeting, PA (US);
Nicholas C. Nicolaides, Plymouth Meeting, PA (US);
Yuhong Zhou, Plymouth Meeting, PA (US);
Qu Dong, Dresher, PA (US);
Kenneth J. Holroyd, Plymouth Meeting, PA (US);
Roy C. Levitt, Plymouth Meeting, PA (US);
W. Lee Maloy, Plymouth Meeting, PA (US);
Jamila Louahed, Plymouth Meeting, PA (US);
Mike McLane, Plymouth Meeting, PA (US);
Nicholas C. Nicolaides, Plymouth Meeting, PA (US);
Yuhong Zhou, Plymouth Meeting, PA (US);
Qu Dong, Dresher, PA (US);
Genaera Corporation, Plymouth Meeting, PA (US);
Abstract
A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.