The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 24, 2007

Filed:

Nov. 21, 2001
Applicants:

Susana Salceda, San Jose, CA (US);

Roberto Macina, San Jose, CA (US);

Herve E. Recipon, San Francisco, CA (US);

Jason Pluta, Mountain View, CA (US);

Yongming Sun, San Jose, CA (US);

Chenghua Liu, San Jose, CA (US);

Inventors:

Susana Salceda, San Jose, CA (US);

Roberto Macina, San Jose, CA (US);

Herve E. Recipon, San Francisco, CA (US);

Jason Pluta, Mountain View, CA (US);

Yongming Sun, San Jose, CA (US);

Chenghua Liu, San Jose, CA (US);

Assignee:

Diadexus, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01); C12N 15/11 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); A61K 31/711 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to newly identified nucleic acids and polypeptides present in normal and neoplastic breast cells, including fragments, variants and derivatives of the nucleic acids and polypeptides. The present invention also relates to antibodies to the polypeptides of the invention, as well as agonists and antagonists of the polypeptides of the invention. The invention also relates to compositions comprising the nucleic acids, polypeptides, antibodies, variants, derivatives, agonists and antagonists of the invention and methods for the use of these compositions. These uses include identifying, diagnosing, monitoring, staging, imaging and treating breast cancer and non-cancerous disease states in breast tissue, identifying breast tissue, monitoring and identifying and/or designing agonists and antagonists of polypeptides of the invention. The uses also include gene therapy, production of transgenic animals and cells, and production of engineered breast tissue for treatment and research.


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