The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2007
Filed:
Oct. 18, 2000
Applicants:
Katsuhiro Komase, Tokyo, JP;
Noriko Suzuki, Tokyo, JP;
Tetsuo Nakayama, Tokyo, JP;
Chikara Aizawa, Saitama, JP;
Inventors:
Katsuhiro Komase, Tokyo, JP;
Noriko Suzuki, Tokyo, JP;
Tetsuo Nakayama, Tokyo, JP;
Chikara Aizawa, Saitama, JP;
Assignee:
The Kitasato Institute, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/155 (2006.01); A61K 39/165 (2006.01);
U.S. Cl.
CPC ...
Abstract
It was found that a mutation of an amino acid at a specific position in the P protein of a morbillivirus gives a temperature-sensitivity character to a virus. By introducing this mutation, a virus to which a temperature-sensitivity character has been introduced can be produced. According to this invention, attenuated viruses useful in the preparation of vaccines can be easily produced.