The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 17, 2007
Filed:
Nov. 19, 2001
David Kay, Wiltshire, GB;
Julian M. C. Golec, Swindon, GB;
David Kay, Wiltshire, GB;
Julian M. C. Golec, Swindon, GB;
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
This invention provides caspase inhibitors having the formula: wherein Ris COH, CHCOH, or esters, amides or isosteres thereof; Rand Rare each independently selected from hydrogen or an optionally substituted C–Caliphatic group; and Rand Rare each independently selected from hydrogen, an optionally substituted C–Caliphatic group, or Rand Rtaken together with the ring to which they are attached form an optionally substituted bicyclic ring. The caspase inhibitors are useful for treating a number of diseases such as cancer, acute inflammatory and autoimmune disorders, ischemic diseases and certain neurodegenerative disorders.