The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2007

Filed:

Nov. 13, 2002
Applicants:

Richard Duane Johnston, Greenfield, IN (US);

Nathan Bryan Mantlo, Brownsburg, IN (US);

Richard Craig Thompson, Frankfort, IN (US);

Inventors:

Richard Duane Johnston, Greenfield, IN (US);

Nathan Bryan Mantlo, Brownsburg, IN (US);

Richard Craig Thompson, Frankfort, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); C07D 271/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to compounds represented by the following structural formula, and pharmaceutically acceptable salts, solvates and hydrates thereof, R1 is selected from the group consisting of hydrogen, substituted or unsubstituted group selected from C1–C8 alkyl, aryl-C0-4-alkyl, heteroaryl-C0-4-alkyl, and C3–C6 cycloalkylaryl-C0-2-alkyl; W is O or S; X is an optionally substituted C1–C5 alkylene linker wherein one carbon atom of the linker may be replaced with O, NH or S; Y is C, O, S, NH or a single bond; E is C(R3)(R4)A or A


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