The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 17, 2007

Filed:

Dec. 15, 2000
Applicants:

Sylvain Cottens, Witterswil, CH;

Barbara Haeberlin, Riehen, CH;

Richard Sedrani, Basel, CH;

Jacky Vonderscher, Riedisheim, FR;

Inventors:

Sylvain Cottens, Witterswil, CH;

Barbara Haeberlin, Riehen, CH;

Richard Sedrani, Basel, CH;

Jacky Vonderscher, Riedisheim, FR;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/66 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides a microemulsion pre-concentrate comprising a difficultly soluble active agent and a carrier medium comprising 1) a hydrophilic phase which comprises dimethylisosorbide and/or a lower alkyl alkanoic ester, 2) a lipophilic phase, and 3) a surfactant. The active agent may be a cyclosporin or a macrolide. In another aspect, this invention provides a pharmaceutical composition for enteral or parenteral administration comprising a macrolide and an acid.


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