The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2007
Filed:
Sep. 14, 2004
Chaim Roifman, Toronto, CA;
Peter Demin, Toronto, CA;
Olga Rounova, Toronto, CA;
Tom Grunberger, Toronto, CA;
Chaim Roifman, Toronto, CA;
Peter Demin, Toronto, CA;
Olga Rounova, Toronto, CA;
Tom Grunberger, Toronto, CA;
The Hospital For Sick Children, Toronto, Ontario, CA;
Abstract
There is described compounds of Formula I, and salts, solvates and hydrates thereof: wherein: R, Rand Rare each independently selected from OH, Calkyl, OCalkyl, OC(O)Calkyl, C(O)OCalkyl, NH, NH—Calkyl, N(Calkyl)(Calkyl), C(O)NHCalkyl, C(O)N(Calkyl)(Calkyl), SH, SCalkyl, NO, CF, OCFand halogen; and Ar is an aromatic or heteroaromatic group chosen from benzene, naphthalene, quinoline, isoquinoline, indole, pyridine, pyrasine, pyrimidine, imidazole, furan and thiophene, unsubstituted or substituted with 1–4 substituents independently selected from OH, Calkyl, Calkoxy, Calkylenedioxy, NH, NH—Calkyl, N(Calkyl)(C)(Calkyl), SH, S—Calkyl, NO, CF, OCFand halogen. The compounds of Formula I are useful: in therapeutic methods and compositions for modulating cell proliferation, in diagnostic assays and as research tools.