The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2007

Filed:

Jul. 03, 2003
Applicants:

Gillian Payne, Waban, MA (US);

Thomas Chittenden, Sudbury, MA (US);

Viktor Goldmakher, Newton, MA (US);

Philip Chun, Malden, MA (US);

Kristin Sneider-mulready, Framingham, MA (US);

Carol A. Vater, Cambridge, MA (US);

Inventors:

Gillian Payne, Waban, MA (US);

Thomas Chittenden, Sudbury, MA (US);

Viktor Goldmakher, Newton, MA (US);

Philip Chun, Malden, MA (US);

Kristin Sneider-Mulready, Framingham, MA (US);

Carol A. Vater, Cambridge, MA (US);

Assignee:

Immunogen Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to antibodies, antibody fragments, conjugates of antibodies and antibody fragments with cytotoxic agents, and hybridomas producing the antibodies and antibody fragments, where the antibodies and antibody fragments recognize extracellular epitopes of plasma membrane proteins that are not released into the extracellular fluid, and to methods for the detection, monitoring and treatment of malignancies such as breast cancer and ovarian cancer using the antibodies, antibody fragments and conjugates.


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