The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2007
Filed:
Apr. 15, 2005
Taeyoung Yoon, Guilford, CT (US);
Ping GE, Durham, CT (US);
Raymond F. Horvath, Guilford, CT (US);
Stėphane Delombaert, Madison, CT (US);
Kevin J. Hodgetts, Killingworth, CT (US);
Dario Doller, Wallingford, CT (US);
Cunyu Zhang, Morrisville, NC (US);
Taeyoung Yoon, Guilford, CT (US);
Ping Ge, Durham, CT (US);
Raymond F. Horvath, Guilford, CT (US);
Stėphane DeLombaert, Madison, CT (US);
Kevin J. Hodgetts, Killingworth, CT (US);
Dario Doller, Wallingford, CT (US);
Cunyu Zhang, Morrisville, NC (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Arylpyrazine compounds are provided, including arylpyrazines that can bind with high affinity and high selectivity to CRFreceptors, including human CRFreceptors. The invention thus includes methods for treatment of disorders and diseases associated with CRFreceptors, including CNS-related disorders and diseases, particularly affective disorders and diseases, and acute and chronic neurological disorders and diseases.