The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2007
Filed:
Oct. 28, 2002
Howland D. T. Jones, Edgewood, NM (US);
David J. Nunez, Albuquerque, NM (US);
Stephen J. Vanslyke, Albuquerque, NM (US);
Robert D. Johnson, Albuquerque, NM (US);
Edward L. Hull, Albuquerque, NM (US);
Howland D. T. Jones, Edgewood, NM (US);
David J. Nunez, Albuquerque, NM (US);
Stephen J. Vanslyke, Albuquerque, NM (US);
Robert D. Johnson, Albuquerque, NM (US);
Edward L. Hull, Albuquerque, NM (US);
InLight Solutions, Inc., Albuquerque, NM (US);
Abstract
Systems and methods for establishing and/or maintaining the accuracy of a multivariate calibration model designed for quantitative optical spectroscopic measurement of attributes or analytes in bodily tissues, bodily fluids or other biological samples, which are particularly useful when the spectral absorbance of the attribute or analyte is small relative to the background. The present invention provides an optically similar reference sample to reduce the effect of instrument or environment variation on the measurement capability of the model. The optically similar reference can be a gel composition having scattering particles suspended therein. The reference gel can be directly applied to a spectroscopic instrument sampler, or can be in a container specifically designed for optimal coupling to a spectroscopic instrument.