The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 10, 2007

Filed:

Sep. 15, 2004
Applicants:

Helmut Schwab, Graz, AT;

Anton Glieder, Gleisdorf, AT;

Christoph Kratky, Graz, AT;

Ingrid Dreveny, Graz, AT;

Rodolfo Bona, Graz, AT;

Peter Pöchlauer, Linz, AT;

Wolfgang Skranc, Vienna, AT;

Herbert Mayrhofer, Engerwitzdorf, AT;

Irma Wirth, Enns, AT;

Rudolf Neuhofer, Engerwitzdorf, AT;

Inventors:

Helmut Schwab, Graz, AT;

Anton Glieder, Gleisdorf, AT;

Christoph Kratky, Graz, AT;

Ingrid Dreveny, Graz, AT;

Rodolfo Bona, Graz, AT;

Peter Pöchlauer, Linz, AT;

Wolfgang Skranc, Vienna, AT;

Herbert Mayrhofer, Engerwitzdorf, AT;

Irma Wirth, Enns, AT;

Rudolf Neuhofer, Engerwitzdorf, AT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12P 1/00 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01); C07C 253/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

New genes containing a DNA sequence coding for hydroxynitrile lyase, which genes can be prepared via a primer combination based on the DNA sequence of the 5'-region of the mdl genes from theand fromand/or a primer 2 based on the 3′-region of the DNA sequences of one of the hydroxynitrile lyase isoenzymes fromor from, subsequent amplification with a DNA polymerase using a DNA from organisms, containing genes coding for hydroxynitrile lyase, as templates and cloning, and also recombinant proteins which can be prepared in suitable host cells by heterologous expression of the DNA sequence of said HNL genes, and proteins and fusion proteins derived therefrom and use of said proteins for preparing (R)- or (S)-cyanohydrins.


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