The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2007
Filed:
Sep. 09, 2002
H. Holden Thorp, Carrboro, NC (US);
Ivana V. Yang, Falls Church, VA (US);
David H. Stewart, Monrovia, MA (US);
John W. Groelke, Raleigh, NC (US);
Veronika A. Szalai, Monrovia, MA (US);
H. Holden Thorp, Carrboro, NC (US);
Ivana V. Yang, Falls Church, VA (US);
David H. Stewart, Monrovia, MA (US);
John W. Groelke, Raleigh, NC (US);
Veronika A. Szalai, Monrovia, MA (US);
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Abstract
A method of detecting two different target molecules through a single electrode is carried out by (a) providing a conductive oxidation-reduction reaction detection electrode; (b) contacting a sample suspected of containing a first and second target molecule to the electrode under conditions in which the first and second target molecules are deposited on the electrode, wherein the first target molecule comprises a first label and the second target molecule comprises a second label; (c) contacting to the electrode a first transition metal complex that oxidizes the first preselected label in a first oxidation-reduction reaction and a second transition metal complex that oxidizes the first and second labels in a second oxidation-reduction reaction, with the first and second oxidation-reduction reactions producing different detectable signals; (d) detecting the presence of the first target molecule by detecting the first oxidation-reduction reaction; and (e) detecting the presence of the second target molecule by detecting the second oxidation-reduction reaction. Devices for carrying out the method are also described.