The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2007
Filed:
Oct. 18, 2002
Martin Vey, Marburg, DE;
Weigand Lang, Coelbe, DE;
Albrecht Groener, Marburg, DE;
Anne Bellon, Marburg, DE;
Martin Vey, Marburg, DE;
Weigand Lang, Coelbe, DE;
Albrecht Groener, Marburg, DE;
Anne Bellon, Marburg, DE;
Aventis Behring GmbH, Marburg, DE;
Abstract
This application includes description of antibodies for specifically detecting prions of human origin and methods for detecting pathogenic prions. In some embodiments, the antibodies bind to an epitope characteristic for a human prion protein which is not found in the prion proteins of other species. In some embodiments, the antibodies are not cross-reactive with cow, Syrian Gold hamster, mouse, or rat prions. The application also includes a conformation-dependent immunoassay method for detecting pathogenic prions in a sample containing a prion (PrP) protein. The PrP protein may be present in a first conformation and a second conformation, such as PrPand PrPin which the two conformations have different binding affinity for the antibody used to detect them.