The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2007

Filed:

Oct. 01, 2002
Applicants:

Bruce A. Ruggeri, West Chester, PA (US);

Margie L. Clapper, Harleysville, PA (US);

Inventors:

Bruce A. Ruggeri, West Chester, PA (US);

Margie L. Clapper, Harleysville, PA (US);

Assignee:

Fox Chase Cancer Center, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/4965 (2006.01); A61K 31/385 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel methods for inhibiting angiogenesis and treating diseases associated with angiogenesis are described. The methods may comprise administering to a patient an effective amount of a 1,2-dithiol-3-thione derivative or metabolite thereof. Preferred compounds for use in the methods include 5-(2-pyrazinyl)-4methyl-1,2-dithiol-3-thione (Oltipraz) and its metabolites.


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