The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2007
Filed:
Sep. 12, 2003
Andrea Liebmann-vinson, Willow Springs, VA (US);
Bryce Chaney, Durham, NC (US);
Kirill Efimenko, Raleigh, NC (US);
Jan Genzer, Raleigh, NC (US);
Andrea Liebmann-Vinson, Willow Springs, VA (US);
Bryce Chaney, Durham, NC (US);
Kirill Efimenko, Raleigh, NC (US);
Jan Genzer, Raleigh, NC (US);
Becton, Dickinson and Company, Franklin Lakes, NJ (US);
North Carolina State University, Raleigh, NC (US);
Abstract
The present invention provides methods of producing a surface with enhanced cell-adhesive properties comprising applying a stress to a polymeric matrix. The strained matrix is then modified by grafting a self-assembled monolayer onto the strained matrix, with the self-assembled monolayer comprising at least one exposed functional group. At least one cell-adhesive molecule can then be coupled to the at least one exposed functional group on the self-assembled monolayer to produce a surface with enhanced cell-adhesive properties.