The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2007
Filed:
Mar. 03, 2003
Gerd Pluschke, Bad Kronzing, DE;
Mueller Markus, Lorrach, DE;
John Robinson, Wermatswil, CH;
Rinaldo Zurbriggen, Schmitten, CH;
Annabelle Freund-renard, Schonenwerd, CH;
Gerd Pluschke, Bad Kronzing, DE;
Mueller Markus, Lorrach, DE;
John Robinson, Wermatswil, CH;
Rinaldo Zurbriggen, Schmitten, CH;
Annabelle Freund-Renard, Schonenwerd, CH;
Pluschke, Gerd et al., Bad Kronzing, DE;
Abstract
The invention presents vaccine formulations comprising highly antigenic epitopes identified within the semi-conserved loop-I of domain III that are capable of eliciting parasite growth inhibitory antibodies. The cyclized or linear peptides can be applied by known adjuvants or be encapsulated by or attached onto the surface of liposomes or virosomes (IRIVs) which serve as human compatible antigen delivery systems. Both cyclized and linear versions of the peptide antigens are surprisingly effective in eliciting immune responses that are cross-reactive with parasite-expressed AMA-1.