The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7196107 B1

PDF
Full Text
Expired
Date of Patent:
Mar. 27, 2007

Filed:

Dec. 18, 2001
Applicants:

Paul John Beswick, Stevenage, GB;

Vipulkumar Patel, Stevenage, GB;

Michael Lawrence Sierra, Les Ulis, FR;

Inventors:

Paul John Beswick, Stevenage, GB;

Vipulkumar Patel, Stevenage, GB;

Michael Lawrence Sierra, Les Ulis, FR;

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/421 (2006.01); C07D 277/20 (2006.01); C07D 263/30 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of formula (I) or pharmaceutically acceptable salts and solvates thereof. Rand Rare independently H or Calkyl, m is 0–3; Xis NH, NCH, O, S; R, Rand Rare independently H, CH, CF, OCH, allyl or halogen; Xis (CRR)n wherein n is 1 or 2; Rand Rindependently represent H, fluorine or Calkyl; Rand Rare independently H, Calkyl or Rand Rtogether with the carbon atom to which they are bonded form a 3–5 membered cycloalklyl ring. Rand Rindependently represent H, fluorine or Calkyl; Ris Calkyl or CF; One of Y and Z is N, the other is S or O; Each Rindependently represents CF, OCH, CHor halogen; y is O, 1, 2, 3, 4, 5. Use of a compound of formula (I) for the manufacture of a medicament for the prevention or treatment of a hPPAR mediated disease or condition, such as dyslipidemia, syndrome X, heart failure, hypercholesteremia, cardiovascular disease, type II diabetes mellitus, type 1 diabetes, insulin resistance hyperlipidemia, obesity, anorexia bulimia, inflammation and anorexia nervosa


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Beswick, Paul. (2007). Thia-and oxazoles and their use as ppars activators (U.S. Patent No. 7196107). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7196107

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