The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2007
Filed:
Dec. 18, 2001
Paul John Beswick, Stevenage, GB;
Vipulkumar Patel, Stevenage, GB;
Michael Lawrence Sierra, Les Ulis, FR;
Paul John Beswick, Stevenage, GB;
Vipulkumar Patel, Stevenage, GB;
Michael Lawrence Sierra, Les Ulis, FR;
SmithKline Beecham Corporation, Philadelphia, PA (US);
Abstract
A compound of formula (I) or pharmaceutically acceptable salts and solvates thereof. Rand Rare independently H or Calkyl, m is 0–3; Xis NH, NCH, O, S; R, Rand Rare independently H, CH, CF, OCH, allyl or halogen; Xis (CRR)n wherein n is 1 or 2; Rand Rindependently represent H, fluorine or Calkyl; Rand Rare independently H, Calkyl or Rand Rtogether with the carbon atom to which they are bonded form a 3–5 membered cycloalklyl ring. Rand Rindependently represent H, fluorine or Calkyl; Ris Calkyl or CF; One of Y and Z is N, the other is S or O; Each Rindependently represents CF, OCH, CHor halogen; y is O, 1, 2, 3, 4, 5. Use of a compound of formula (I) for the manufacture of a medicament for the prevention or treatment of a hPPAR mediated disease or condition, such as dyslipidemia, syndrome X, heart failure, hypercholesteremia, cardiovascular disease, type II diabetes mellitus, type 1 diabetes, insulin resistance hyperlipidemia, obesity, anorexia bulimia, inflammation and anorexia nervosa