The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2007

Filed:

Nov. 04, 2003
Applicants:

Joseph L. Duffy, Cranford, NJ (US);

Elizabeth Louise Campbell, North Brunswick, NJ (US);

Brian A. Kirk, Basking Ridge, NJ (US);

Rui Liang, East Brunswick, NJ (US);

James R. Tata, Westfield, NJ (US);

Kevin T. Chapman, Scotch Plains, NJ (US);

Zenon Konteatis, Chatham Township, NJ (US);

Inventors:

Joseph L. Duffy, Cranford, NJ (US);

Elizabeth Louise Campbell, North Brunswick, NJ (US);

Brian A. Kirk, Basking Ridge, NJ (US);

Rui Liang, East Brunswick, NJ (US);

James R. Tata, Westfield, NJ (US);

Kevin T. Chapman, Scotch Plains, NJ (US);

Zenon Konteatis, Chatham Township, NJ (US);

Assignee:

Merck & Co., Inc, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61K 31/381 (2006.01); C07D 333/38 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention addresses substituted cyanothiophene derivatives of the formula I: as well as compositions containing such compounds and methods of treatment. The compounds in the present invention are glucagon antagonists. The compounds block the action of glucagon at its receptor and thereby decrease the levels of plasma glucose providing a treatment of diabetes.


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