The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2007

Filed:

Jul. 30, 2003
Applicants:

Benny C. Askew, Jr., Newbury Park, CA (US);

Frenel F. DE Morin, Thousand Oaks, CA (US);

Andrew Hague, Camarillo, CA (US);

Ellen Laber, Ventura, CA (US);

Aiwen LI, Westlake Village, CA (US);

Gang Liu, Oak Park, CA (US);

Patricia Lopez, West Hills, CA (US);

Rana Nomak, Westlake Village, CA (US);

Vincent Santora, Carlsbad, CA (US);

Christopher Tegley, Thousand Oaks, CA (US);

Kevin Yang, San Gabriel, CA (US);

Inventors:

Benny C. Askew, Jr., Newbury Park, CA (US);

Frenel F. De Morin, Thousand Oaks, CA (US);

Andrew Hague, Camarillo, CA (US);

Ellen Laber, Ventura, CA (US);

Aiwen Li, Westlake Village, CA (US);

Gang Liu, Oak Park, CA (US);

Patricia Lopez, West Hills, CA (US);

Rana Nomak, Westlake Village, CA (US);

Vincent Santora, Carlsbad, CA (US);

Christopher Tegley, Thousand Oaks, CA (US);

Kevin Yang, San Gabriel, CA (US);

Assignee:

Amgen, Inc., Thousand Oakes, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Selected novel urea compounds are effective for prophylaxis and treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stoke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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