The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2007
Filed:
Jul. 17, 2003
Cleo J. Chivikas Connolly, Livonia, MI (US);
Christopher James Deur, Ann Arbor, MI (US);
James Marino Hamby, Ann Arbor, MI (US);
Denton Wade Hoyer, Dexter, MI (US);
Chris Limberakis, Saline, MI (US);
Jessica Elizabeth Reed, Ann Arbor, MI (US);
Mel Conrad Schroeder, Dexter, MI (US);
Clarke Taylor, Ann Arbor, MI (US);
Cleo J. Chivikas Connolly, Livonia, MI (US);
Christopher James Deur, Ann Arbor, MI (US);
James Marino Hamby, Ann Arbor, MI (US);
Denton Wade Hoyer, Dexter, MI (US);
Chris Limberakis, Saline, MI (US);
Jessica Elizabeth Reed, Ann Arbor, MI (US);
Mel Conrad Schroeder, Dexter, MI (US);
Clarke Taylor, Ann Arbor, MI (US);
Warner-Lambert Company, Morris Plains, NJ (US);
Abstract
This invention provides phenyl-substituted pyrimidopyrimidines, dihydropyrimido-pyrimidines, pyridopyrimidines, naphthyridines, and pyridopyrazines of the general formula: that inhibit cyclin-dependent kinase and tyrosine kinase enzymes, methods and intermediate compounds for their synthesis, as well as pharmaceutical compositions and methods for their use in treating, inhibiting or preventing maladies associated with cell proliferative disorders, including angiogenesis, atherosclerosis, restenosis, and cancer.