The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
Nov. 23, 2005
Applicants:
Noboru Yamaji, Ibaraki, JP;
Kouichi Nishimura, Ibaraki, JP;
Kunitake Abe, Ibaraki, JP;
Inventors:
Assignee:
Astellas Pharma Inc., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 1/21 (2006.01); C12N 5/06 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
Abstract
A novel polypeptide, a polynucleotide encoding this polypeptide, an expression vector comprising this polynucleotide, a cell transfected with the expression vector, an antibody binding to the above polypeptide, a convenient screening method for obtaining an agent for treating joint diseases, and a process for manufacturing a pharmaceutical composition for treating joint diseases are disclosed. The polypeptide is a novel aggrecanase causative of joint diseases (particularly an OA disease).