The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2007

Filed:

Sep. 24, 2003
Applicants:

Gerald F. Sigler, Carmel, IN (US);

Raymond A. Hui, Indianapolis, IN (US);

Ina Deras, San Diego, CA (US);

Richard Terry Root, Fishers, IN (US);

Mitali Ghoshal, Nobleville, IN (US);

Erasmus Huber, Finning, DE;

Herbert W. Von Der Eltz, Weilheim, DE;

Sigrun Metz, Munich, DE;

Peter Kern, Penzberg, DE;

Inventors:

Gerald F. Sigler, Carmel, IN (US);

Raymond A. Hui, Indianapolis, IN (US);

Ina Deras, San Diego, CA (US);

Richard Terry Root, Fishers, IN (US);

Mitali Ghoshal, Nobleville, IN (US);

Erasmus Huber, Finning, DE;

Herbert W. Von Der Eltz, Weilheim, DE;

Sigrun Metz, Munich, DE;

Peter Kern, Penzberg, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); C07K 17/06 (2006.01); C07D 239/10 (2006.01); G01N 33/532 (2006.01); G01N 33/533 (2006.01);
U.S. Cl.
CPC ...
Abstract

Activated haptens useful for generating immunogens to HIV protease inhibitors, immunogens useful for producing antibodies to HIV protease inhibitors, and antibodies and labeled conjugates useful in immunoassays for HIV protease inhibitors. The novel haptens feature an activated functionality at the central, non-terminal hydroxyl group common to all HIV protease inhibitors, e.g., saquinavir, nelfinavir, indinavir, amprenavir, ritonavir, lopinavir, and atazanavir.


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