The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
Nov. 14, 2003
Xian-ping LU, Guangdong, CN;
Zhibin LI, Guangdong, CN;
Chenzhong Liao, Guangdong, CN;
Leming Shi, Guangdong, CN;
Zhende Liu, Guangdong, CN;
Zhiqiang Ning, Guangdong, CN;
Song Shan, Guangdong, CN;
Tuo Deng, Guangdong, CN;
Baoshun MA, Guangdong, CN;
Xian-Ping Lu, Guangdong, CN;
Zhibin Li, Guangdong, CN;
Chenzhong Liao, Guangdong, CN;
Leming Shi, Guangdong, CN;
Zhende Liu, Guangdong, CN;
Zhiqiang Ning, Guangdong, CN;
Song Shan, Guangdong, CN;
Tuo Deng, Guangdong, CN;
Baoshun Ma, Guangdong, CN;
Chipscreen Biosciences, Ltd., , CN;
Abstract
Disclosed are the preparation and pharmaceutical use of novel noncyclic 1,3-dicarbonyl compounds of formula I, wherein ring A, ring B, R, R, R, R, R, X, Y, Z, Q, Ar and n are as defined in the specification. These compounds, as peroxisome proliferator-activated receptor (PPAR) dual agonists for both RXR/PPARgamma and RXR/PPARalpha heterodimers, are useful in the treatment and/or prevention of type 2 diabetes and associated metabolic syndrome such as hypertension, obesity, insulin resistance, hyperlipidemia, hyperglycemia, hypercholesterolemia, atherosclerosis, coronary artery disease, and other cardiovascular disorders