The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2007

Filed:

Nov. 09, 2004
Applicants:

Yoshio Ogino, Tsukuba, JP;

Hideki Kurihara, Tsukuba, JP;

Kenji Matsuda, Tsukuba, JP;

Tomoshige Numazawa, Tsukuba, JP;

Norikazu Otake, Tsukuba, JP;

Kazuhito Noguchi, Tsukuba, JP;

Inventors:

Yoshio Ogino, Tsukuba, JP;

Hideki Kurihara, Tsukuba, JP;

Kenji Matsuda, Tsukuba, JP;

Tomoshige Numazawa, Tsukuba, JP;

Norikazu Otake, Tsukuba, JP;

Kazuhito Noguchi, Tsukuba, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/46 (2006.01); C07D 451/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds which exhibit selective muscarinic Mreceptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); Ar signifies optionally substituted aryl or heteroaryl; Band Bsignify aliphatic hydrocarbon; Rsignifies fluorine-substituted cycloalkyl; R, Rand Rsignify lower alkyl, single bond or alkylene bonded to B, or Rand Rare united to signify alkylene; Rand Rsignify hydrogen, lower alkyl, or a single bond or alkylene bonded to B; Rsignifies hydrogen, lower alkyl or a group expressed as —N(R)R; and Xsignifies an anion].


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