The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
May. 30, 2003
Vilas H. Dahanukar, Edison, NJ (US);
Hoa N. Nguyen, Dayton, NJ (US);
Cecilia A. Orr, Clark, NJ (US);
Funcheng Zhang, Edison, NJ (US);
Ilia A. Zavialov, East Windwor, NJ (US);
Kevin Klopfer, Flemington, NJ (US);
Jeffrey M. Skell, Holliston, MA (US);
Albert W. Buchholz, Jr., Bridgewater, NJ (US);
Craig D. Boyle, Branchburg, NJ (US);
Vilas H. Dahanukar, Edison, NJ (US);
Hoa N. Nguyen, Dayton, NJ (US);
Cecilia A. Orr, Clark, NJ (US);
Funcheng Zhang, Edison, NJ (US);
Ilia A. Zavialov, East Windwor, NJ (US);
Kevin Klopfer, Flemington, NJ (US);
Jeffrey M. Skell, Holliston, MA (US);
Albert W. Buchholz, Jr., Bridgewater, NJ (US);
Craig D. Boyle, Branchburg, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
Crystalline polymorphs of 1-ethyl-3,7-dihydro-8-[(1R,2R) -(hydroxycyclopentyl)amino]-3-(2-hydroxyethyl)-7-[(3-bromo-4-methoxyphenyl)methyl]-1H-Purine-2,6-dione in Form 1 and Form 2, which exhibit x-ray powder diffraction profiles substantially the same as those shown in FIGS.and, respectively, and which exhibit differential scanning calorimtery profiles substantially the same as those shown in FIGS.and, respectively, and are represented by the formula: Pharmaceutical compositions comprising the polymorph Form 1 or 2 of Compound 13 and at least one excipient or carrier, and methods of using the polymorph Form 1 or 2 of Compound 13 to treat a variety of physiological disorders, such as erectile dysfunction.