The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
Dec. 01, 2003
Stephen Peter East, Abingdon, GB;
Stephen Peter East, Abingdon, GB;
Vernalis (Oxford) Limited, , GB;
Abstract
Compounds of formula (I) have antibacterial activity; wherein Q represents a radical of formula —N(OH)CH(═O) or formula —C(═O)NH(OH); Y represents —C(═O)—, —C(═S)—, —S(═O)—, or —SO—; Rrepresents hydrogen, C–Calkyl or C–Calkyl substituted by one or more halogen atoms, or, except when Q is a radical of formula —N(OH)CH(═O), a hydroxy, C–Calkoxy, C–Calkenyloxy, halogen, amino, C–Calkylamino, or di-(C–Calkyl)amino group; Rrepresents a substituted or unsubstituted C–Calkyl, C–Calkyl-O—C–Calkyl, C–Calkyl-S—C–Calkyl, cycloalkyl(C–Calkyl)-, aryl(C–Calkyl)-, heterocyclyl(C–Calkyl)-, or RRN—C–Calkyl group wherein Rrepresents hydrogen or C–Calkyl and Rrepresents C–Calkyl, or RRN-represents a cyclic amino group; Rand Rtaken together with the nitrogen atoms to which they are respectively attached form a saturated heterocyclic ring of from 4 to 7 ring atoms, which may be fused to a second carbocyclic or heterocyclic ring, either of which rings may optionally be substituted; and A represents a primary, secondary or tertiary amino group or a group —R, —OR, wherein Ris a substituted or unsubstituted C–Calkyl, C–Calkenyl, C–Calkynyl, cycloalkyl, aryl, heterocyclyl, C–Calkyl-O—C–Calkyl, C–Calkyl-S—C–Calkyl, cycloalkyl(C–Calkyl)-, heterocyclic(C–Calkyl, aryl(C–Calkyl)-or RRN—C–Calkyl group wherein Rrepresents hydrogen or C–Calkyl and Rrepresents C–Calkyl, or RRN-represents a cyclic amino group