The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
Dec. 04, 1998
Applicants:
David C. Kaslow, Rancho Santa Fe, CA (US);
Takafumi Tsuboi, Shigenobu-cho, JP;
Motomi Torii, Tobe-cho, JP;
Inventors:
David C. Kaslow, Rancho Santa Fe, CA (US);
Takafumi Tsuboi, Shigenobu-cho, JP;
Motomi Torii, Tobe-cho, JP;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to novel methods and compositions for blocking transmission ofwhich cause malaria. In particular, Pvs25 and Pvs28 polypeptides, variants, including deglycosylated forms, and fusion proteins thereof, are disclosed which, when administered to a susceptible organism, induce an immune response against a 25 kD and 28 kD protein, respectively, on the surface ofzygotes and ookinetes. This immune response in the susceptible organism can block transmission of malaria.