The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 20, 2007

Filed:

Oct. 11, 2001
Applicants:

Geoffrey Wayne Krissansen, Auckland, NZ;

Jagat Rakesh Kanwar, Auckland, NZ;

Inventors:

Geoffrey Wayne Krissansen, Auckland, NZ;

Jagat Rakesh Kanwar, Auckland, NZ;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/05 (2006.01); A61K 31/66 (2006.01); A61K 31/498 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to methods for the treatment or prevention of central nervous system (CNS) cell damage and functional damage in mammals due to demyelinating disease including multiple sclerosis. More specifically, the invention comprises a method of treating a demyelinating disease of the CNS in a mammal, the method comprising co-administering to the mammal, either sequentially or simultaneously, GPE or analogues or peptidomimetics or a prodrug thereof, or a pharmaceutically acceptable salt thereof, and an AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate)/kainate antagonist, or a pharmaceutically acceptable salt thereof, and an anti-inflammatory agent.


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