The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 20, 2007
Filed:
Dec. 08, 2000
Brian R. Murphy, Bethesda, MD (US);
Peter L. Collins, Silver Spring, MD (US);
Alexander C. Schmidt, Washington, DC (US);
Anna P. Durbin, Takoma Park, MD (US);
Mario H. Skiadopoulos, Potomac, MD (US);
Tao Tao, Bethesda, MD (US);
Brian R. Murphy, Bethesda, MD (US);
Peter L. Collins, Silver Spring, MD (US);
Alexander C. Schmidt, Washington, DC (US);
Anna P. Durbin, Takoma Park, MD (US);
Mario H. Skiadopoulos, Potomac, MD (US);
Tao Tao, Bethesda, MD (US);
Abstract
Chimeric parainfluenza viruses (PIVs) incorporate a PIV vector genome or antigenome and one or more antigenic determinant(s) of a heterologous PIV or non-PIV pathogen. These chimeric viruses are infectious and attenuated in humans and other mammals and are useful in vaccine formulations for eliciting an immune responses against one or more PIVs, or against a PIV and non-PIV pathogen. Also provided are isolated polynucleotide molecules and vectors incorporating a chimeric Ply genome or antigenome which includes a partial or complete PIV vector genome or antigenome combined or integrated with one or more heterologous gene(s) or genome segment(s) encoding antigenic determinant(s) of a heterologous PIV or non-PIV pathogen.