The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2007

Filed:

Sep. 29, 2005
Applicants:

Richard D. Cummings, Edmond, OK (US);

Rodger P. Mcever, Oklahoma City, OK (US);

Inventors:

Richard D. Cummings, Edmond, OK (US);

Rodger P. McEver, Oklahoma City, OK (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 3/06 (2006.01); A61K 31/70 (2006.01); A61K 38/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds, compositions and methods for treating conditions characterized by leukocyte rolling are described. The compounds contain glycosulfopeptide structures comprising sulfated tyrosines and sialyated, fucosylated N-acetyllactosamino glycans. The glycosulfopeptides may be conjugated or complexed to other compounds for enhancing serum half-life or for controlled release, for example. Examples of conditions treated include inflammation, ischemia-reperfusion injury, rheumatoid arthritis, atherosclerosis, leukocyte-mediated lung injury, restenosis, and thrombosis.


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