The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2007
Filed:
Feb. 10, 2004
Shubh D. Sharma, Cranbury, NJ (US);
Yi-qun Shi, East Brunswick, NJ (US);
Zhijun Wu, Plainsboro, NJ (US);
Ramesh Rajpurohit, Hillsboro, NJ (US);
Shubh D. Sharma, Cranbury, NJ (US);
Yi-Qun Shi, East Brunswick, NJ (US);
Zhijun Wu, Plainsboro, NJ (US);
Ramesh Rajpurohit, Hillsboro, NJ (US);
Palatin Technologies, Inc., Cranbury, NJ (US);
Abstract
Melanocortin receptor-specific pyrrolidine compounds having the structure: and stereoisomer and pharmaceutically acceptable salts thereof, where R, R, and Rare as described in the specification, preferably where Ris a D-amino acid with at least one substituted or unsubstituted phenyl or naphthyl aromatic ring, and where Roptionally further includes an amine capping group or from one to three additional amino acid residues, optionally with an amine capping group, which compounds are agonists, antagonists or mixed agonists and antagonists at one or more melanocortin receptors, and having utility in the treatment of melanocortin receptor-related disorders and conditions. Methods of synthesis of compounds of structure (I), pharmaceutical compositions containing a compound of structure (I) and methods relating to the use thereof are also disclosed.