The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2007
Filed:
Mar. 19, 2002
Matthias Schwarz, Thonex, CH;
Anna Quattropani, Geneva, CH;
Alexander Scheer, Versoix, CH;
Jerome Dorbais, Annecy, FR;
Vincent Pomel, Groisy, FR;
Matthias Schwarz, Thonex, CH;
Anna Quattropani, Geneva, CH;
Alexander Scheer, Versoix, CH;
Jerome Dorbais, Annecy, FR;
Vincent Pomel, Groisy, FR;
Applied Research Systems ARS Holding NV, Curacao, AN;
Abstract
The present invention is related to the use of pyrrolidine esters of formula (I) for the treatment and/or prevention of premature labor, premature birth and dysmenorrhea. In particular, the present invention is related to the use of pyrrolidine esters of formula (I) to modulate, notably to antagonize the oxytocin receptor. The present invention is furthermore related to novel pyrrolidine esters. X is selected from the group consisting of CRR, NOR, NNRR; R is selected from the group comprising or consisting of C–Calkyl, C–Calkenyl, C–Calkynyl, saturated or unsaturated 3–8-membered cycloalkyl which may contain 1 to 3 heteroatoms selected of N, O, S, aryl, heteroaryl, C–C-alkyl aryl, C–C-alkyl heteroaryl. Ris selected from the group comprising or consisting of C–C-alkyl, C–C-alkenyl, C–C-alkynyl, aryl, heteroaryl, 3–8-membered cycloalkyl, acyl, C–C-alkyl aryl, C–C-alkyl heteroaryl, said cycloalkyl or aryl or heteroaryl groups may be fused with 1–2 further cycloalkyl or aryl or heteroaryl group