The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2007

Filed:

Oct. 10, 2003
Applicants:

Matthew Lee Brown, San Francisco, CA (US);

Mui Cheung, Durham, NC (US);

Scott Howard Dickerson, Durham, NC (US);

Cassandra Gauthier, Longmont, CO (US);

Philip Anthony Harris, Durham, NC (US);

Robert Neil Hunter, Durham, NC (US);

Gregory Pacofsky, Raleigh, NC (US);

Michael Robert Peel, Durham, NC (US);

Jeffrey Alan Stafford, San Diego, CA (US);

Inventors:

Matthew Lee Brown, San Francisco, CA (US);

Mui Cheung, Durham, NC (US);

Scott Howard Dickerson, Durham, NC (US);

Cassandra Gauthier, Longmont, CO (US);

Philip Anthony Harris, Durham, NC (US);

Robert Neil Hunter, Durham, NC (US);

Gregory Pacofsky, Raleigh, NC (US);

Michael Robert Peel, Durham, NC (US);

Jeffrey Alan Stafford, San Diego, CA (US);

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/541 (2006.01); A61K 31/5355 (2006.01); A61K 31/496 (2006.01); A61K 31/4525 (2006.01); A61K 31/443 (2006.01); A61K 31/421 (2006.01); C07D 417/10 (2006.01); C07D 413/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

Oxazole derivatives, which are useful as VEGFR2, CDK2, and CDK4 inhibitors are described herein. The described invention also includes methods of making such oxazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.


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