The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2007
Filed:
Apr. 27, 2005
Jian Chen, Sunnyvale, CA (US);
Holger Keim, Wyckoff, NJ (US);
Hshiou-ting Liu, Milpitas, CA (US);
Yi Feng Zheng, Wilmington, DE (US);
Yali Yang, Bear, DE (US);
Cathy K. Worley, Washington, DC (US);
Jian Chen, Sunnyvale, CA (US);
Holger Keim, Wyckoff, NJ (US);
Hshiou-ting Liu, Milpitas, CA (US);
Yi Feng Zheng, Wilmington, DE (US);
Yali Yang, Bear, DE (US);
Cathy K. Worley, Washington, DC (US);
Dade Behring Inc., Deerfield, IL (US);
Abstract
Compounds are disclosed comprising a moiety, such as a poly(amino acid), a non-poly(amino acid) label moiety, or a non-poly(amino acid) immunogenic carrier, linked to a sirolimus compound at position 26 or at position 32. Such sirolimus compounds comprising an immunogenic carrier can be employed to raise both polyclonal and monoclonal antibodies to the sirolimus compound. Polyclonal antibodies are also disclosed, which are raised against a compound wherein a moiety, such as a poly(amino acid), a non-poly(amino acid) label moiety, or a non-poly(amino acid) immunogenic carrier, is linked to a sirolimus compound at position 32. The above antibodies and sirolimus compounds comprising a label can be used in assays for the detection of sirolimus compounds.