The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 13, 2007
Filed:
Nov. 05, 2002
Applicants:
Michael A. Apicella, Solon, IA (US);
Andrew Preston, Cambridge, GB;
Inventors:
Michael A. Apicella, Solon, IA (US);
Andrew Preston, Cambridge, GB;
Assignee:
University of Iowa Research Foundation, Iowa City, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/21 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention discloses a mutanthaving extensive membrane blebbing, both an indicium and a cause of virulence in the gonococcus and meningococcus. Methods are disclosed for making and characterizing the mutant, bmrRS. Methods are disclosed for isolating bmrRS membranes for use as a vaccine. Methods are also disclosed for the use of the mutant for determining the virulence of clinical samples ofand. Methods are also disclosed for the screening of antibiotics targeted to virulent