The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 13, 2007

Filed:

May. 05, 2003
Applicants:

Larry A. Sklar, Albuquerque, NM (US);

Tione Buranda, Albuquerque, NM (US);

Daniel Cimino, Tijeras, NM (US);

Alex T. Key, Albuquerque, NM (US);

Richard Neubig, Scio, MI (US);

Peter C. Simons, Albuquerque, NM (US);

Eric R. Prossnitz, Albuquerque, NM (US);

Mei Shi, Albuquerque, NM (US);

Inventors:

Larry A. Sklar, Albuquerque, NM (US);

Tione Buranda, Albuquerque, NM (US);

Daniel Cimino, Tijeras, NM (US);

Alex T. Key, Albuquerque, NM (US);

Richard Neubig, Scio, MI (US);

Peter C. Simons, Albuquerque, NM (US);

Eric R. Prossnitz, Albuquerque, NM (US);

Mei Shi, Albuquerque, NM (US);

Assignees:

STC.UNM, Albuquerque, NM (US);

Univeristy of Michigan, Ann Arbor, MI (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/52 (2006.01); G01N 33/566 (2006.01); C12N 1/20 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a general approach for G protein coupled receptors that may be used to define agonists and antagonists, and the specificity of receptor coupling to G protein subunits. Methods of the present invention use small volumes (microliters) and are compatible with high throughput flow cytometry. When assays of the present invention are multiplexed, the specificity of the interactions of a receptor with many G proteins may be determined simultaneously.


Find Patent Forward Citations

Loading…