The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2007
Filed:
Aug. 11, 2000
Markus Schweitzer, Frankfurt am Main, DE;
Norbert Windhab, Hofheim am Taunus, DE;
John R. Havens, Arlington, MA (US);
Thomas J. Onofrey, Poway, CA (US);
Charles Greef, Boulder, CO (US);
Daguang Wang, Carlsbad, CA (US);
Markus Schweitzer, Frankfurt am Main, DE;
Norbert Windhab, Hofheim am Taunus, DE;
John R. Havens, Arlington, MA (US);
Thomas J. Onofrey, Poway, CA (US);
Charles Greef, Boulder, CO (US);
Daguang Wang, Carlsbad, CA (US);
Nanogen Recognomics GmbH, Frankfurt, DE;
Abstract
Biomolecules are provided having multiple binding sites for attachment to a substrate surface. The multiple attachment sites may be produced directly on the biomolecule or through use of branched phosphoramidite moieties that can be added in multiple to form dendritic structures which can in turn provide attachment sites for substrate binding moieties. Substrate binding moieties may include noncovalent binding moieties. For covalent binding moieties oligonucleotides containing hydrazides are provided. These hydrazides can be introduced via protected building blocks such as phosphoramidites or via building blocks containing precursor forms of such hydrazides.