The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 2007
Filed:
Dec. 23, 2003
Mark M. Staveski, Taunton, MA (US);
Robert J. Miller, E. Bridgewater, MA (US);
Sharon R. Nahill, Belmont, MA (US);
Mark M. Staveski, Taunton, MA (US);
Robert J. Miller, E. Bridgewater, MA (US);
Sharon R. Nahill, Belmont, MA (US);
Genzyme Corporation, Cambridge, MA (US);
Abstract
The present invention provides compositions and their use in the treatment of inflammatory diseases caused by T-cell proliferation such as sepsis, inflammatory bowel diseases, autoimmune encephalomyelitis, or lupus. The compositions comprise disubstituted ureas of Formulas I, II, III or IV:R—NH—CO—NH-Q-RFormula I:Et-NH—CO—NH-Q-R:  Formula (II)Et-NH—CO—NH—(CH)—NRR:  Formula (III)MeN—(CH)—NH—CO—NH-Q-R.  Formula (IV)