The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 06, 2007

Filed:

Feb. 28, 2001
Applicants:

Evan Y. Snyder, Jamaica Plain, MA (US);

Xandra O. Breakefield, Newton Center, MA (US);

Karen S. Aboody, Needham, MA (US);

Ulrich Herrlinger, Tuebingen, DE;

William P. Lynch, Ravenna, OH (US);

Inventors:

Evan Y. Snyder, Jamaica Plain, MA (US);

Xandra O. Breakefield, Newton Center, MA (US);

Karen S. Aboody, Needham, MA (US);

Ulrich Herrlinger, Tuebingen, DE;

William P. Lynch, Ravenna, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 48/00 (2006.01); C12N 5/08 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is based upon a surprising finding that stem cells, more particularly neural stem cells, can migrate throughout a brain tumor and track metastatic brain tumor cells. The invention provides a method for treating brain tumors by administering genetically engineered neural stem cells in an individual affected by brain tumors. The invention also provides a method of preparing genetically engineered neural stem cells and a composition comprising genetically engineered neural stem cells in a pharmaceutically acceptable carrier.


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