The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2007
Filed:
Jul. 08, 2004
Applicants:
James A. Sikorski, Alpharetta, GA (US);
Jayraz Luchoomun, Lilburn, GA (US);
Charles Q. Meng, Alpharetta, GA (US);
Uday Saxena, Atlanta, GA (US);
Inventors:
James A. Sikorski, Alpharetta, GA (US);
Jayraz Luchoomun, Lilburn, GA (US);
Charles Q. Meng, Alpharetta, GA (US);
Uday Saxena, Atlanta, GA (US);
Assignee:
Atherogenics, Inc., Alpharetta, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/255 (2006.01); C07C 323/00 (2006.01); C07C 229/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
It has been discovered that certain selected ethers of probucol, and their pharmaceutically acceptable salts or prodrugs, are useful for increasing circulating HDL cholesterol. These compounds may also improve HDL functionality by (a) increasing clearance of cholesteryl esters, (b) increasing HDL-particle affinity for hepatic cell surface receptors or (c) increasing the half life of apoAI-HDL.