The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2007
Filed:
Nov. 10, 2005
Michael F. Summers, Ellicott City, MD (US);
Atul Agarwal, Hamden, CT (US);
Xi Chen, Killingworth, CT (US);
Milind Deshpande, Madison, CT (US);
Michael F. Summers, Ellicott City, MD (US);
Atul Agarwal, Hamden, CT (US);
Xi Chen, Killingworth, CT (US);
Milind Deshpande, Madison, CT (US);
Other;
Abstract
Substituted aryl aminomethyl thiazole ureas and analogues thereof that act as inhibitors of viral capsid formation, including HIV capsid formation, are provided here. Generally the virus capsid formation inhibitors described herein are compounds of Formula I wherein the variables A, R, R, R, R, X, Y, Z, A, A, A, R, R, R, and Rare defined herein. Pharmaceutical compositions comprising such compounds and methods of treating animals infected with a virus having a capsid protein are provided herein. Methods of using such compounds to treat human patients infected with an HIV virus and reducing the mortality of AIDS are also provided herein.