The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 20, 2007

Filed:

Dec. 18, 2002
Applicants:

Bruce Eaton, Cary, NC (US);

Theodore M. Tarasow, Longmont, CO (US);

Dan Nieuwlandt, Longmont, CO (US);

Torin Dewey, Longmont, CO (US);

Inventors:

Bruce Eaton, Cary, NC (US);

Theodore M. Tarasow, Longmont, CO (US);

Dan Nieuwlandt, Longmont, CO (US);

Torin Dewey, Longmont, CO (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 205/085 (2006.01); C07D 227/087 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods for identifying (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives with anti-PBP2a activity. The method involves the selection of RNA biocatalysts that promote the formation of (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives with anti-PBP2a activity from component reactants. The invention also provides novel (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives with anti-PBP2a activity identified by these methods. The invention also provides RNA biocatalysts that are capable of catalyzing the formation of (3-amino-2-oxo-azetidin-1-yl) acetic acid derivatives from component reactants.


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